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[单选题]A 2-year-old child presents with poor weight gain, sparse hair, unusual face with sunken eyes, and skin that reddens markedly in sunlight. A diagnosis of Cockayne syndrome (MIM*216400) is considered and studies of DNA synthesis are undertaken. In vitro assay of labeled thymidine incorporation reveals decreased levels of DNA synthesis compared to controls, but normal-sized labeled DNA fragments. The addition of protein extract from normal cells gently heated to inactivate DNA polymerase restores DNA synthesis in Cockayne cells to normal. Which of the following enzymes used in DNA replication is most likely to be defective in Cockayne syndrome?EGl答案窝(daanwo.com)-大学作业答案分享平台
A、Unwinding proteinsEGl答案窝(daanwo.com)-大学作业答案分享平台
B、DNA-directed RNA polymeraseEGl答案窝(daanwo.com)-大学作业答案分享平台
C、DNA polymerase IEGl答案窝(daanwo.com)-大学作业答案分享平台
D、DNA ligaseEGl答案窝(daanwo.com)-大学作业答案分享平台
E、DNA-directed DNA polymeraseEGl答案窝(daanwo.com)-大学作业答案分享平台
 
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